Evaluation of a Platinum–Acridine Anticancer Agent and Its Liposomal Formulation in an In Vivo Model of Lung Adenocarcinoma

Liposomal formulations have been developed for a highly cytotoxic platinum–acridine agent, [PtCl(pn)(C(18)H(21)N(4))](NO(3))(2) (PA, pn = propane-1,3-diamine), and fully characterized. Nanoliposomes consisting of hydrogenated soybean phosphatidylcholine (HSPC), 1,2-dihexadecanoyl-sn-glycero-3-phosph...

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Detalhes bibliográficos
Publicado no:ChemMedChem
Main Authors: Ding, Song, Hackett, Christopher L., Liu, Fang, Hackett, Ryan G., Bierbach, Ulrich
Formato: Artigo
Idioma:Inglês
Publicado em: 2020
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC8057267/
https://ncbi.nlm.nih.gov/pubmed/32975041
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/cmdc.202000637
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