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HspQ Functions as a Unique Specificity-Enhancing Factor for the AAA+ Lon Protease

The AAA+ Lon protease is conserved from bacteria to humans, performs crucial roles in protein homeostasis, and is implicated in bacterial pathogenesis and human disease. We investigated how Lon selectively degrades specific substrates among a diverse array of potential targets. We report the discove...

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Detalhes bibliográficos
Publicado no:Mol Cell
Main Authors: Puri, Neha, Karzai, A. Wali
Formato: Artigo
Idioma:Inglês
Publicado em: 2017
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC8054221/
https://ncbi.nlm.nih.gov/pubmed/28575662
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.molcel.2017.05.016
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