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HspQ Functions as a Unique Specificity-Enhancing Factor for the AAA+ Lon Protease

The AAA+ Lon protease is conserved from bacteria to humans, performs crucial roles in protein homeostasis, and is implicated in bacterial pathogenesis and human disease. We investigated how Lon selectively degrades specific substrates among a diverse array of potential targets. We report the discove...

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Bibliografiske detaljer
Udgivet i:Mol Cell
Main Authors: Puri, Neha, Karzai, A. Wali
Format: Artigo
Sprog:Inglês
Udgivet: 2017
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC8054221/
https://ncbi.nlm.nih.gov/pubmed/28575662
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.molcel.2017.05.016
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