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X-ray Crystallographic Snapshots of Substrate Binding in the Active Site of Histone Deacetylase 10
Histone deacetylase 10 (HDAC10) is a zinc-dependent polyamine deacetylase enriched in the cytosol of eukaryotic cells. The active site of HDAC10 contains catalytic residues conserved in other HDAC isozymes that function as lysine deacetylases: Y307 assists the zinc ion in polarizing the substrate ca...
Tallennettuna:
| Julkaisussa: | Biochemistry |
|---|---|
| Päätekijät: | , |
| Aineistotyyppi: | Artigo |
| Kieli: | Inglês |
| Julkaistu: |
2021
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| Aiheet: | |
| Linkit: | https://ncbi.nlm.nih.gov/pmc/articles/PMC8053227/ https://ncbi.nlm.nih.gov/pubmed/33449614 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/acs.biochem.0c00936 |
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