QSM is an imaging biomarker for chronic glial activation in multiple sclerosis lesions

BACKGROUND: Inflammation in chronic active lesions occurs behind a closed blood–brain barrier and cannot be detected with MRI. Activated microglia are highly enriched for iron and can be visualized with quantitative susceptibility mapping (QSM), an MRI technique used to delineate iron. OBJECTIVE: To...

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Gorde:
Xehetasun bibliografikoak
Argitaratua izan da:Ann Clin Transl Neurol
Egile Nagusiak: Gillen, Kelly M., Mubarak, Mayyan, Park, Calvin, Ponath, Gerald, Zhang, Shun, Dimov, Alexey, Levine‐Ritterman, Maya, Toro, Steven, Huang, Weiyuan, Amici, Stephanie, Kaunzner, Ulrike W., Gauthier, Susan A., Guerau‐de‐Arellano, Mireia, Wang, Yi, Nguyen, Thanh D., Pitt, David
Formatua: Artigo
Hizkuntza:Inglês
Argitaratua: John Wiley and Sons Inc. 2021
Gaiak:
Research Articles
Sarrera elektronikoa:https://ncbi.nlm.nih.gov/pmc/articles/PMC8045922/
https://ncbi.nlm.nih.gov/pubmed/33704933
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/acn3.51338
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