Magnetic susceptibility increases as diamagnetic molecules break down: myelin digestion during multiple sclerosis lesion formation contributes to increase on QSM

BACKGROUND: The pathological processes in the first weeks of multiple sclerosis (MS) lesion formation include myelin digestion that breaks chemical bonds in myelin lipid layers. This can increase lesion magnetic susceptibility, which is a potentially useful biomarker in MS patient management, but no...

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Detalhes bibliográficos
Publicado no:J Magn Reson Imaging
Main Authors: Deh, Kofi, Ponath, Gerald D., Molvi, Zaki, Parel, Gian-Carlo T., Gillen, Kelly M., Zhang, Shun, Nguyen, Thanh D., Spincemaille, Pascal, Ma, Yinghua, Gupta, Ajay, Gauthier, Susan A., Pitt, David, Wang, Yi
Formato: Artigo
Idioma:Inglês
Publicado em: 2018
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6129234/
https://ncbi.nlm.nih.gov/pubmed/29517817
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/jmri.25997
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