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Significance and In Vivo Detection of Iron-Laden Microglia in White Matter Multiple Sclerosis Lesions

Microglia are resident immune cells that fulfill protective and homeostatic functions in the central nervous system (CNS) but may also promote neurotoxicity in the aged brain and in chronic disease. In multiple sclerosis (MS), an autoimmune demyelinating disease of the CNS, microglia and macrophages...

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Bibliografiske detaljer
Udgivet i:Front Immunol
Main Authors: Gillen, Kelly M., Mubarak, Mayyan, Nguyen, Thanh D., Pitt, David
Format: Artigo
Sprog:Inglês
Udgivet: Frontiers Media S.A. 2018
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5826076/
https://ncbi.nlm.nih.gov/pubmed/29515576
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fimmu.2018.00255
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