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Significance and In Vivo Detection of Iron-Laden Microglia in White Matter Multiple Sclerosis Lesions

Microglia are resident immune cells that fulfill protective and homeostatic functions in the central nervous system (CNS) but may also promote neurotoxicity in the aged brain and in chronic disease. In multiple sclerosis (MS), an autoimmune demyelinating disease of the CNS, microglia and macrophages...

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Veröffentlicht in:Front Immunol
Hauptverfasser: Gillen, Kelly M., Mubarak, Mayyan, Nguyen, Thanh D., Pitt, David
Format: Artigo
Sprache:Inglês
Veröffentlicht: Frontiers Media S.A. 2018
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5826076/
https://ncbi.nlm.nih.gov/pubmed/29515576
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fimmu.2018.00255
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