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Significance and In Vivo Detection of Iron-Laden Microglia in White Matter Multiple Sclerosis Lesions

Microglia are resident immune cells that fulfill protective and homeostatic functions in the central nervous system (CNS) but may also promote neurotoxicity in the aged brain and in chronic disease. In multiple sclerosis (MS), an autoimmune demyelinating disease of the CNS, microglia and macrophages...

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Detalhes bibliográficos
Publicado no:Front Immunol
Main Authors: Gillen, Kelly M., Mubarak, Mayyan, Nguyen, Thanh D., Pitt, David
Formato: Artigo
Idioma:Inglês
Publicado em: Frontiers Media S.A. 2018
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5826076/
https://ncbi.nlm.nih.gov/pubmed/29515576
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fimmu.2018.00255
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