Enhanced astrocyte responses are driven by a genetic risk allele associated with multiple sclerosis

Epigenetic annotation studies of genetic risk variants for multiple sclerosis (MS) implicate dysfunctional lymphocytes in MS susceptibility; however, the role of central nervous system (CNS) cells remains unclear. We investigated the effect of the risk variant, rs7665090(G), located near NFKB1, on a...

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Dades bibliogràfiques
Publicat a:Nat Commun
Autors principals: Ponath, Gerald, Lincoln, Matthew R., Levine-Ritterman, Maya, Park, Calvin, Dahlawi, Somiah, Mubarak, Mayyan, Sumida, Tomokazu, Airas, Laura, Zhang, Shun, Isitan, Cigdem, Nguyen, Thanh D., Raine, Cedric S., Hafler, David A., Pitt, David
Format: Artigo
Idioma:Inglês
Publicat: Nature Publishing Group UK 2018
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Article
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC6297228/
https://ncbi.nlm.nih.gov/pubmed/30559390
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41467-018-07785-8
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