TFEB Links MYC Signaling to Epigenetic Control of Myeloid Differentiation and Acute Myeloid Leukemia

MYC oncoproteins regulate transcription of genes directing cell proliferation, metabolism, and tumorigenesis. A variety of alterations drive MYC expression in acute myeloid leukemia (AML), and enforced MYC expression in hematopoietic progenitors is sufficient to induce AML. Here we report that AML a...

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Bibliografiset tiedot
Julkaisussa:Blood Cancer Discov
Päätekijät: Yun, Seongseok, Vincelette, Nicole D., Yu, Xiaoqing, Watson, Gregory W., Fernandez, Mario R., Yang, Chunying, Hitosugi, Taro, Cheng, Chia-Ho, Freischel, Audrey R., Zhang, Ling, Li, Weimin, Hou, Hsinan, Schaub, Franz X., Vedder, Alexis R., Cen, Ling, McGraw, Kathy L., Moon, Jungwon, Murphy, Daniel J., Ballabio, Andrea, Kaufmann, Scott H., Berglund, Anders E., Cleveland, John L.
Aineistotyyppi: Artigo
Kieli:Inglês
Julkaistu: American Association for Cancer Research 2020
Aiheet:
Research Articles
Linkit:https://ncbi.nlm.nih.gov/pmc/articles/PMC8043621/
https://ncbi.nlm.nih.gov/pubmed/33860275
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1158/2643-3230.BCD-20-0029
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