TFEB Links MYC Signaling to Epigenetic Control of Myeloid Differentiation and Acute Myeloid Leukemia

MYC oncoproteins regulate transcription of genes directing cell proliferation, metabolism, and tumorigenesis. A variety of alterations drive MYC expression in acute myeloid leukemia (AML), and enforced MYC expression in hematopoietic progenitors is sufficient to induce AML. Here we report that AML a...

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Bibliografski detalji
Izdano u:Blood Cancer Discov
Glavni autori: Yun, Seongseok, Vincelette, Nicole D., Yu, Xiaoqing, Watson, Gregory W., Fernandez, Mario R., Yang, Chunying, Hitosugi, Taro, Cheng, Chia-Ho, Freischel, Audrey R., Zhang, Ling, Li, Weimin, Hou, Hsinan, Schaub, Franz X., Vedder, Alexis R., Cen, Ling, McGraw, Kathy L., Moon, Jungwon, Murphy, Daniel J., Ballabio, Andrea, Kaufmann, Scott H., Berglund, Anders E., Cleveland, John L.
Format: Artigo
Jezik:Inglês
Izdano: American Association for Cancer Research 2020
Teme:
Research Articles
Online pristup:https://ncbi.nlm.nih.gov/pmc/articles/PMC8043621/
https://ncbi.nlm.nih.gov/pubmed/33860275
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1158/2643-3230.BCD-20-0029
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