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STUB1 regulates TFEB‐induced autophagy–lysosome pathway

TFEB is a master regulator for transcription of genes involved in autophagy and lysosome biogenesis. Activity of TFEB is inhibited upon its serine phosphorylation by mTOR. The overall mechanisms by which TFEB activity in the cell is regulated are not well elucidated. Specifically, the mechanisms of...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Veröffentlicht in:EMBO J
Hauptverfasser: Sha, Youbao, Rao, Lang, Settembre, Carmine, Ballabio, Andrea, Eissa, N Tony
Format: Artigo
Sprache:Inglês
Veröffentlicht: John Wiley and Sons Inc. 2017
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5579343/
https://ncbi.nlm.nih.gov/pubmed/28754656
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.15252/embj.201796699
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