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STUB1 regulates TFEB‐induced autophagy–lysosome pathway

TFEB is a master regulator for transcription of genes involved in autophagy and lysosome biogenesis. Activity of TFEB is inhibited upon its serine phosphorylation by mTOR. The overall mechanisms by which TFEB activity in the cell is regulated are not well elucidated. Specifically, the mechanisms of...

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Bibliografische gegevens
Gepubliceerd in:EMBO J
Hoofdauteurs: Sha, Youbao, Rao, Lang, Settembre, Carmine, Ballabio, Andrea, Eissa, N Tony
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: John Wiley and Sons Inc. 2017
Onderwerpen:
Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5579343/
https://ncbi.nlm.nih.gov/pubmed/28754656
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.15252/embj.201796699
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