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Lysosomal calcium signaling regulates autophagy via calcineurin and TFEB
The view of the lysosome as the terminal end of cellular catabolic pathways has been challenged by recent studies showing a central role of this organelle in the control of cell function. Here we show that a lysosomal Ca(2+) signaling mechanism controls the activities of the phosphatase calcineurin...
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| Publicado no: | Nat Cell Biol |
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| Main Authors: | , , , , , , , , , , , , , , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2015
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4801004/ https://ncbi.nlm.nih.gov/pubmed/25720963 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/ncb3114 |
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