Loading...

STUB1 regulates TFEB‐induced autophagy–lysosome pathway

TFEB is a master regulator for transcription of genes involved in autophagy and lysosome biogenesis. Activity of TFEB is inhibited upon its serine phosphorylation by mTOR. The overall mechanisms by which TFEB activity in the cell is regulated are not well elucidated. Specifically, the mechanisms of...

Full description

Saved in:
Bibliographic Details
Published in:EMBO J
Main Authors: Sha, Youbao, Rao, Lang, Settembre, Carmine, Ballabio, Andrea, Eissa, N Tony
Format: Artigo
Language:Inglês
Published: John Wiley and Sons Inc. 2017
Subjects:
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC5579343/
https://ncbi.nlm.nih.gov/pubmed/28754656
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.15252/embj.201796699
Tags: Add Tag
No Tags, Be the first to tag this record!