TFEB Links MYC Signaling to Epigenetic Control of Myeloid Differentiation and Acute Myeloid Leukemia

MYC oncoproteins regulate transcription of genes directing cell proliferation, metabolism, and tumorigenesis. A variety of alterations drive MYC expression in acute myeloid leukemia (AML), and enforced MYC expression in hematopoietic progenitors is sufficient to induce AML. Here we report that AML a...

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Detalhes bibliográficos
Publicado no:Blood Cancer Discov
Main Authors: Yun, Seongseok, Vincelette, Nicole D., Yu, Xiaoqing, Watson, Gregory W., Fernandez, Mario R., Yang, Chunying, Hitosugi, Taro, Cheng, Chia-Ho, Freischel, Audrey R., Zhang, Ling, Li, Weimin, Hou, Hsinan, Schaub, Franz X., Vedder, Alexis R., Cen, Ling, McGraw, Kathy L., Moon, Jungwon, Murphy, Daniel J., Ballabio, Andrea, Kaufmann, Scott H., Berglund, Anders E., Cleveland, John L.
Formato: Artigo
Idioma:Inglês
Publicado em: American Association for Cancer Research 2020
Assuntos:
Research Articles
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC8043621/
https://ncbi.nlm.nih.gov/pubmed/33860275
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1158/2643-3230.BCD-20-0029
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