Harnessing the polyamine transport system to treat BRAF inhibitor-resistant melanoma

BRAF mutations are present in over half of all melanoma tumors. Although BRAF inhibitors significantly improve survival of patients with metastatic melanoma, recurrences occur within several months. We previously reported that BRAF mutant melanoma cells are more sensitive to a novel arylmethyl-polya...

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Vydáno v:Cancer Biol Ther
Hlavní autoři: Alexander, Eric T., El Naggar, Olivia, Fahey, Erin, Mariner, Kelsey, Donnelly, Julia, Wolfgang, Katelyn, Phanstiel, Otto, Gilmour, Susan K
Médium: Artigo
Jazyk:Inglês
Vydáno: Taylor & Francis 2021
Témata:
Research Paper
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC8043175/
https://ncbi.nlm.nih.gov/pubmed/33602034
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1080/15384047.2021.1883185
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