Harnessing the polyamine transport system to treat BRAF inhibitor-resistant melanoma

BRAF mutations are present in over half of all melanoma tumors. Although BRAF inhibitors significantly improve survival of patients with metastatic melanoma, recurrences occur within several months. We previously reported that BRAF mutant melanoma cells are more sensitive to a novel arylmethyl-polya...

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Detalles Bibliográficos
Publicado en:Cancer Biol Ther
Autores principales: Alexander, Eric T., El Naggar, Olivia, Fahey, Erin, Mariner, Kelsey, Donnelly, Julia, Wolfgang, Katelyn, Phanstiel, Otto, Gilmour, Susan K
Formato: Artigo
Lenguaje:Inglês
Publicado: Taylor & Francis 2021
Materias:
Research Paper
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC8043175/
https://ncbi.nlm.nih.gov/pubmed/33602034
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1080/15384047.2021.1883185
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