Harnessing the polyamine transport system to treat BRAF inhibitor-resistant melanoma

BRAF mutations are present in over half of all melanoma tumors. Although BRAF inhibitors significantly improve survival of patients with metastatic melanoma, recurrences occur within several months. We previously reported that BRAF mutant melanoma cells are more sensitive to a novel arylmethyl-polya...

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Bibliografische gegevens
Gepubliceerd in:Cancer Biol Ther
Hoofdauteurs: Alexander, Eric T., El Naggar, Olivia, Fahey, Erin, Mariner, Kelsey, Donnelly, Julia, Wolfgang, Katelyn, Phanstiel, Otto, Gilmour, Susan K
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: Taylor & Francis 2021
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Research Paper
Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC8043175/
https://ncbi.nlm.nih.gov/pubmed/33602034
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1080/15384047.2021.1883185
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