Harnessing the polyamine transport system to treat BRAF inhibitor-resistant melanoma

BRAF mutations are present in over half of all melanoma tumors. Although BRAF inhibitors significantly improve survival of patients with metastatic melanoma, recurrences occur within several months. We previously reported that BRAF mutant melanoma cells are more sensitive to a novel arylmethyl-polya...

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Bibliographische Detailangaben
Veröffentlicht in:Cancer Biol Ther
Hauptverfasser: Alexander, Eric T., El Naggar, Olivia, Fahey, Erin, Mariner, Kelsey, Donnelly, Julia, Wolfgang, Katelyn, Phanstiel, Otto, Gilmour, Susan K
Format: Artigo
Sprache:Inglês
Veröffentlicht: Taylor & Francis 2021
Schlagworte:
Research Paper
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC8043175/
https://ncbi.nlm.nih.gov/pubmed/33602034
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1080/15384047.2021.1883185
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