Harnessing the polyamine transport system to treat BRAF inhibitor-resistant melanoma

BRAF mutations are present in over half of all melanoma tumors. Although BRAF inhibitors significantly improve survival of patients with metastatic melanoma, recurrences occur within several months. We previously reported that BRAF mutant melanoma cells are more sensitive to a novel arylmethyl-polya...

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Bibliografiske detaljer
Udgivet i:Cancer Biol Ther
Main Authors: Alexander, Eric T., El Naggar, Olivia, Fahey, Erin, Mariner, Kelsey, Donnelly, Julia, Wolfgang, Katelyn, Phanstiel, Otto, Gilmour, Susan K
Format: Artigo
Sprog:Inglês
Udgivet: Taylor & Francis 2021
Fag:
Research Paper
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC8043175/
https://ncbi.nlm.nih.gov/pubmed/33602034
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1080/15384047.2021.1883185
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