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Evaluation of Polyamine Transport Inhibitors in a Drosophila Epithelial Model Suggests the Existence of Multiple Transport Systems

Increased polyamine biosynthesis activity and an active polyamine transport system are characteristics of many cancer cell lines and polyamine depletion has been shown to be a viable anticancer strategy. Polyamine levels can be depleted by difluoromethylornithine (DFMO), an inhibitor of the key poly...

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Bibliografiske detaljer
Udgivet i:Med Sci (Basel)
Main Authors: Wang, Minpei, Phanstiel, Otto, von Kalm, Laurence
Format: Artigo
Sprog:Inglês
Udgivet: MDPI 2017
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5753656/
https://ncbi.nlm.nih.gov/pubmed/29135915
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/medsci5040027
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