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Identification of Trypanosoma cruzi Polyamine Transport Inhibitors by Computational Drug Repurposing
Trypanosoma cruzi is the causative agent of Chagas disease, a parasitic infection endemic in Latin America. In T. cruzi the transport of polyamines is essential because this organism is unable to synthesize these compounds de novo. Therefore, the uptake of polyamines from the extracellular medium is...
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| Publicado no: | Front Med (Lausanne) |
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| Main Authors: | , , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Frontiers Media S.A.
2019
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6857147/ https://ncbi.nlm.nih.gov/pubmed/31781568 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fmed.2019.00256 |
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