Trypanocidal Effect of Isotretinoin through the Inhibition of Polyamine and Amino Acid Transporters in Trypanosoma cruzi

Polyamines are essential compounds to all living organisms and in the specific case of Trypanosoma cruzi, the causative agent of Chagas disease, they are exclusively obtained through transport processes since this parasite is auxotrophic for polyamines. Previous works reported that retinol acetate i...

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Detalhes bibliográficos
Publicado no:PLoS Negl Trop Dis
Main Authors: Reigada, Chantal, Valera-Vera, Edward A., Sayé, Melisa, Errasti, Andrea E., Avila, Carla C., Miranda, Mariana R., Pereira, Claudio A.
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2017
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5371382/
https://ncbi.nlm.nih.gov/pubmed/28306713
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pntd.0005472
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