Trypanocidal Effect of Isotretinoin through the Inhibition of Polyamine and Amino Acid Transporters in Trypanosoma cruzi

Polyamines are essential compounds to all living organisms and in the specific case of Trypanosoma cruzi, the causative agent of Chagas disease, they are exclusively obtained through transport processes since this parasite is auxotrophic for polyamines. Previous works reported that retinol acetate i...

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Pubblicato in:PLoS Negl Trop Dis
Autori principali: Reigada, Chantal, Valera-Vera, Edward A., Sayé, Melisa, Errasti, Andrea E., Avila, Carla C., Miranda, Mariana R., Pereira, Claudio A.
Natura: Artigo
Lingua:Inglês
Pubblicazione: Public Library of Science 2017
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Research Article
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC5371382/
https://ncbi.nlm.nih.gov/pubmed/28306713
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pntd.0005472
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