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Trypanocidal Effect of Isotretinoin through the Inhibition of Polyamine and Amino Acid Transporters in Trypanosoma cruzi

Polyamines are essential compounds to all living organisms and in the specific case of Trypanosoma cruzi, the causative agent of Chagas disease, they are exclusively obtained through transport processes since this parasite is auxotrophic for polyamines. Previous works reported that retinol acetate i...

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Detalles Bibliográficos
Publicado en:PLoS Negl Trop Dis
Main Authors: Reigada, Chantal, Valera-Vera, Edward A., Sayé, Melisa, Errasti, Andrea E., Avila, Carla C., Miranda, Mariana R., Pereira, Claudio A.
Formato: Artigo
Idioma:Inglês
Publicado: Public Library of Science 2017
Assuntos:
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC5371382/
https://ncbi.nlm.nih.gov/pubmed/28306713
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pntd.0005472
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