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Polyamine Transport as a Target for Treatment of Pneumocystis Pneumonia
Polyamine levels are greatly increased in alveolar macrophages (AMs) during Pneumocystis pneumonia (PCP), leading to increased production of H(2)O(2), which causes AMs to undergo apoptosis. One of the mechanisms by which polyamine levels in AMs are elevated is enhanced uptake of exogenous polyamines...
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| Autores principales: | , , , , , , , |
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| Formato: | Artigo |
| Lenguaje: | Inglês |
| Publicado: |
American Society for Microbiology (ASM)
2009
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| Materias: | |
| Acceso en línea: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2786323/ https://ncbi.nlm.nih.gov/pubmed/19805570 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/AAC.00662-09 |
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