Pneumocystis Mediates Overexpression of Antizyme Inhibitor Resulting in Increased Polyamine Levels and Apoptosis in Alveolar Macrophages

Pneumocystis pneumonia (PcP) is the most common opportunistic disease in immunocompromised patients. Alveolar macrophages are responsible for the clearance of Pneumocystis organisms; however, they undergo a high rate of apoptosis during PcP due to increased intracellular polyamine levels. In this st...

Popoln opis

Shranjeno v:
Bibliografske podrobnosti
Main Authors: Liao, Chung-Ping, Lasbury, Mark E., Wang, Shao-Hung, Zhang, Chen, Durant, Pamela J., Murakami, Yasuko, Matsufuji, Senya, Lee, Chao-Hung
Format: Artigo
Jezik:Inglês
Izdano: American Society for Biochemistry and Molecular Biology 2009
Teme:
Molecular Basis of Cell and Developmental Biology
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC2658110/
https://ncbi.nlm.nih.gov/pubmed/19158080
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M805787200
Oznake: Označite
Brez oznak, prvi označite!

Podobne knjige/članki