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Evaluation of Polyamine Transport Inhibitors in a Drosophila Epithelial Model Suggests the Existence of Multiple Transport Systems

Increased polyamine biosynthesis activity and an active polyamine transport system are characteristics of many cancer cell lines and polyamine depletion has been shown to be a viable anticancer strategy. Polyamine levels can be depleted by difluoromethylornithine (DFMO), an inhibitor of the key poly...

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Bibliografiska uppgifter
I publikationen:Med Sci (Basel)
Huvudupphovsmän: Wang, Minpei, Phanstiel, Otto, von Kalm, Laurence
Materialtyp: Artigo
Språk:Inglês
Publicerad: MDPI 2017
Ämnen:
Länkar:https://ncbi.nlm.nih.gov/pmc/articles/PMC5753656/
https://ncbi.nlm.nih.gov/pubmed/29135915
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/medsci5040027
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