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Coevolution underlies GPCR-G protein selectivity and functionality
G protein-coupled receptors (GPCRs) regulate diverse physiological events, which makes them as the major targets for many approved drugs. G proteins are downstream molecules that receive signals from GPCRs and trigger cell responses. The GPCR-G protein selectivity mechanism on how they properly and...
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| Foilsithe in: | Sci Rep |
|---|---|
| Main Authors: | , , , , |
| Formáid: | Artigo |
| Teanga: | Inglês |
| Foilsithe: |
Nature Publishing Group UK
2021
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| Ábhair: | |
| Rochtain Ar Líne: | https://ncbi.nlm.nih.gov/pmc/articles/PMC8041822/ https://ncbi.nlm.nih.gov/pubmed/33846507 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-021-87251-6 |
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