Assembly of a GPCR-G protein Complex

The activation of G proteins by G protein-coupled receptors (GPCRs) underlies the majority of transmembrane signaling by hormones and neurotransmitters. Recent structures of GPCR-G protein complexes obtained by crystallography and cryo-electron microscopy (cryo-EM) reveal similar interactions betwee...

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Publicado en:Cell
Autores principales: Du, Yang, Duc, Nguyen Minh, Rasmussen, Søren G. F., Hilger, Daniel, Kubiak, Xavier, Wang, Liwen, Bohon, Jennifer, Kim, Hee Ryung, Wegrecki, Marcin, Asuru, Awuri, Jeong, Kyung Min, Lee, Jeongmi, Chance, Mark R., Lodowski, David T., Kobilka, Brian K., Chung, Ka Young
Formato: Artigo
Lenguaje:Inglês
Publicado: 2019
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Article
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC6763313/
https://ncbi.nlm.nih.gov/pubmed/31080064
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.cell.2019.04.022
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