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Assembly of a GPCR-G protein Complex

The activation of G proteins by G protein-coupled receptors (GPCRs) underlies the majority of transmembrane signaling by hormones and neurotransmitters. Recent structures of GPCR-G protein complexes obtained by crystallography and cryo-electron microscopy (cryo-EM) reveal similar interactions betwee...

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Bibliografiska uppgifter
I publikationen:Cell
Huvudupphovsmän: Du, Yang, Duc, Nguyen Minh, Rasmussen, Søren G. F., Hilger, Daniel, Kubiak, Xavier, Wang, Liwen, Bohon, Jennifer, Kim, Hee Ryung, Wegrecki, Marcin, Asuru, Awuri, Jeong, Kyung Min, Lee, Jeongmi, Chance, Mark R., Lodowski, David T., Kobilka, Brian K., Chung, Ka Young
Materialtyp: Artigo
Språk:Inglês
Publicerad: 2019
Ämnen:
Länkar:https://ncbi.nlm.nih.gov/pmc/articles/PMC6763313/
https://ncbi.nlm.nih.gov/pubmed/31080064
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.cell.2019.04.022
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