Assembly of a GPCR-G protein Complex

The activation of G proteins by G protein-coupled receptors (GPCRs) underlies the majority of transmembrane signaling by hormones and neurotransmitters. Recent structures of GPCR-G protein complexes obtained by crystallography and cryo-electron microscopy (cryo-EM) reveal similar interactions betwee...

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Udgivet i:Cell
Main Authors: Du, Yang, Duc, Nguyen Minh, Rasmussen, Søren G. F., Hilger, Daniel, Kubiak, Xavier, Wang, Liwen, Bohon, Jennifer, Kim, Hee Ryung, Wegrecki, Marcin, Asuru, Awuri, Jeong, Kyung Min, Lee, Jeongmi, Chance, Mark R., Lodowski, David T., Kobilka, Brian K., Chung, Ka Young
Format: Artigo
Sprog:Inglês
Udgivet: 2019
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Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6763313/
https://ncbi.nlm.nih.gov/pubmed/31080064
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.cell.2019.04.022
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