The structure of a minimum amyloid fibril core formed by necroptosis-mediating RHIM of human RIPK3

Receptor-interacting protein kinases 3 (RIPK3), a central node in necroptosis, polymerizes in response to the upstream signals and then activates its downstream mediator to induce cell death. The active polymeric form of RIPK3 has been indicated as the form of amyloid fibrils assembled via its RIP h...

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Detalhes bibliográficos
Publicado no:Proc Natl Acad Sci U S A
Main Authors: Wu, Xialian, Ma, Yeyang, Zhao, Kun, Zhang, Jing, Sun, Yunpeng, Li, Yichen, Dong, Xingqi, Hu, Hong, Liu, Jing, Wang, Jian, Zhang, Xia, Li, Bing, Wang, Huayi, Li, Dan, Sun, Bo, Lu, Junxia, Liu, Cong
Formato: Artigo
Idioma:Inglês
Publicado em: National Academy of Sciences 2021
Assuntos:
Biological Sciences
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC8040640/
https://ncbi.nlm.nih.gov/pubmed/33790016
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.2022933118
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