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COP9 Signalosome Suppresses RIPK1-RIPK3 Mediated Cardiomyocyte Necroptosis in Mice
BACKGROUND: Mechanisms governing the induction of heart failure by the impairment of autophagy and the ubiquitin-proteasome system (UPS) and the molecular pathways to cardiomyocyte (CM) necrosis remain incompletely understood. COPS8 is an essential subunit of the COP9 signalosome (CSN), a key regula...
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| Publicado no: | Circ Heart Fail |
|---|---|
| Main Authors: | , , , , , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2020
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC7438278/ https://ncbi.nlm.nih.gov/pubmed/32578441 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1161/CIRCHEARTFAILURE.120.006996 |
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