Tumor necrosis factor alpha-mediated inflammation and remodeling of the extracellular matrix underlies aortic stiffening induced by the common chemotherapeutic agent doxorubicin

Aortic stiffening is a major independent risk factor for cardiovascular diseases, kidney dysfunction and cognitive impairment. Doxorubicin (DOXO) chemotherapy-treated cancer survivors have greater aortic stiffness relative to healthy controls, but the mechanisms by which DOXO induces arterial stiffe...

Ausführliche Beschreibung

Gespeichert in:
Bibliographische Detailangaben
Veröffentlicht in:Hypertension
Hauptverfasser: Clayton, Zachary S., Brunt, Vienna E., Hutton, David A., Casso, Abigail G., Ziemba, Brian P., Melov, Simon, Campisi, Judith, Seals, Douglas R.
Format: Artigo
Sprache:Inglês
Veröffentlicht: 2021
Schlagworte:
Article
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC8035245/
https://ncbi.nlm.nih.gov/pubmed/33719511
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1161/HYPERTENSIONAHA.120.16759
Tags: Tag hinzufügen
Keine Tags, Fügen Sie den ersten Tag hinzu!

Ähnliche Einträge