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Androgens regulate ovarian gene expression by balancing Ezh2-Jmjd3 mediated H3K27me3 dynamics

Conventionally viewed as male hormone, androgens play a critical role in female fertility. Although androgen receptors (AR) are transcription factors, to date very few direct transcriptional targets of ARs have been identified in the ovary. Using mouse models, this study provides three critical insi...

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Bibliografiske detaljer
Udgivet i:PLoS Genet
Main Authors: Roy, Sambit, Huang, Binbin, Sinha, Niharika, Wang, Jianrong, Sen, Aritro
Format: Artigo
Sprog:Inglês
Udgivet: Public Library of Science 2021
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC8034747/
https://ncbi.nlm.nih.gov/pubmed/33784295
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pgen.1009483
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