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Androgens regulate ovarian gene expression by balancing Ezh2-Jmjd3 mediated H3K27me3 dynamics

Conventionally viewed as male hormone, androgens play a critical role in female fertility. Although androgen receptors (AR) are transcription factors, to date very few direct transcriptional targets of ARs have been identified in the ovary. Using mouse models, this study provides three critical insi...

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Detalhes bibliográficos
Publicado no:PLoS Genet
Main Authors: Roy, Sambit, Huang, Binbin, Sinha, Niharika, Wang, Jianrong, Sen, Aritro
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2021
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC8034747/
https://ncbi.nlm.nih.gov/pubmed/33784295
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pgen.1009483
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