EZH2/H3K27Me3 and phosphorylated EZH2 predict chemotherapy response and prognosis in ovarian cancer

BACKGROUND: EZH2 acts as an oncogene through canonical pathway EZH2/H3K27Me3 and uncanonical pathway pAkt1/pS21EZH2 in many solid tumors including ovarian cancer. However, the clinical value of EZH2/H3K27Me3 and pAkt1/pS21EZH2 remain unclear. In the current study, we aim to investigate the correlati...

Disgrifiad llawn

Wedi'i Gadw mewn:
Manylion Llyfryddiaeth
Cyhoeddwyd yn:PeerJ
Prif Awduron: Sun, Si, Yang, Qiang, Cai, E, Huang, Bangxing, Ying, Feiquan, Wen, Yiping, Cai, Jing, Yang, Ping
Fformat: Artigo
Iaith:Inglês
Cyhoeddwyd: PeerJ Inc. 2020
Pynciau:
Bioinformatics
Mynediad Ar-lein:https://ncbi.nlm.nih.gov/pmc/articles/PMC7227641/
https://ncbi.nlm.nih.gov/pubmed/32435534
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.7717/peerj.9052
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