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Androgens regulate ovarian gene expression by balancing Ezh2-Jmjd3 mediated H3K27me3 dynamics

Conventionally viewed as male hormone, androgens play a critical role in female fertility. Although androgen receptors (AR) are transcription factors, to date very few direct transcriptional targets of ARs have been identified in the ovary. Using mouse models, this study provides three critical insi...

詳細記述

保存先:
書誌詳細
出版年:PLoS Genet
主要な著者: Roy, Sambit, Huang, Binbin, Sinha, Niharika, Wang, Jianrong, Sen, Aritro
フォーマット: Artigo
言語:Inglês
出版事項: Public Library of Science 2021
主題:
オンライン・アクセス:https://ncbi.nlm.nih.gov/pmc/articles/PMC8034747/
https://ncbi.nlm.nih.gov/pubmed/33784295
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pgen.1009483
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