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Developmental programming: prenatal testosterone-induced epigenetic modulation and its effect on gene expression in sheep ovary

Maternal perturbations or sub-optimal conditions during fetal development can predispose the offspring to diseases in adult life. Animal and human studies show that prenatal androgen excess may be an underlying cause of polycystic ovary syndrome (PCOS) later in life. In women, PCOS is a common ferti...

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Detalhes bibliográficos
Publicado no:Biol Reprod
Main Authors: Sinha, Niharika, Roy, Sambit, Huang, Binbin, Wang, Jianrong, Padmanabhan, Vasantha, Sen, Aritro
Formato: Artigo
Idioma:Inglês
Publicado em: Oxford University Press 2020
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7186781/
https://ncbi.nlm.nih.gov/pubmed/31930385
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/biolre/ioaa007
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