Developmental programming: prenatal testosterone-induced epigenetic modulation and its effect on gene expression in sheep ovary

Maternal perturbations or sub-optimal conditions during fetal development can predispose the offspring to diseases in adult life. Animal and human studies show that prenatal androgen excess may be an underlying cause of polycystic ovary syndrome (PCOS) later in life. In women, PCOS is a common ferti...

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Shranjeno v:
Bibliografske podrobnosti
izdano v:Biol Reprod
Main Authors: Sinha, Niharika, Roy, Sambit, Huang, Binbin, Wang, Jianrong, Padmanabhan, Vasantha, Sen, Aritro
Format: Artigo
Jezik:Inglês
Izdano: Oxford University Press 2020
Teme:
Research Article
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC7186781/
https://ncbi.nlm.nih.gov/pubmed/31930385
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/biolre/ioaa007
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