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Differential Therapeutic Effects of FXR Activation, sEH Inhibition, and Dual FXR/sEH Modulation in NASH in Diet-Induced Obese Mice

[Image: see text] Nonalcoholic fatty liver disease (NAFLD) is an epidemic chronic liver disease and may progress over nonalcoholic steatohepatitis (NASH) to liver cirrhosis and hepatocellular carcinoma. The multiple metabolic, environmental, and genetic factors that are involved in NAFLD/NASH pathog...

詳細記述

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書誌詳細
出版年:ACS Pharmacol Transl Sci
主要な著者: Helmstädter, Moritz, Schmidt, Jurema, Kaiser, Astrid, Weizel, Lilia, Proschak, Ewgenij, Merk, Daniel
フォーマット: Artigo
言語:Inglês
出版事項: American Chemical Society 2021
オンライン・アクセス:https://ncbi.nlm.nih.gov/pmc/articles/PMC8033765/
https://ncbi.nlm.nih.gov/pubmed/33860214
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/acsptsci.1c00041
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