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The cGAS–STING pathway as a therapeutic target in inflammatory diseases

The cGAS–STING signalling pathway has emerged as a key mediator of inflammation in the settings of infection, cellular stress and tissue damage. Underlying this broad involvement of the cGAS–STING pathway is its capacity to sense and regulate the cellular response towards microbial and host-derived...

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Dades bibliogràfiques
Publicat a:Nat Rev Immunol
Autors principals: Decout, Alexiane, Katz, Jason D., Venkatraman, Shankar, Ablasser, Andrea
Format: Artigo
Idioma:Inglês
Publicat: Nature Publishing Group UK 2021
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC8029610/
https://ncbi.nlm.nih.gov/pubmed/33833439
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41577-021-00524-z
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