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The cGAS–STING pathway as a therapeutic target in inflammatory diseases

The cGAS–STING signalling pathway has emerged as a key mediator of inflammation in the settings of infection, cellular stress and tissue damage. Underlying this broad involvement of the cGAS–STING pathway is its capacity to sense and regulate the cellular response towards microbial and host-derived...

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Detalhes bibliográficos
Publicado no:Nat Rev Immunol
Main Authors: Decout, Alexiane, Katz, Jason D., Venkatraman, Shankar, Ablasser, Andrea
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group UK 2021
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC8029610/
https://ncbi.nlm.nih.gov/pubmed/33833439
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41577-021-00524-z
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