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The cGAS–STING pathway as a therapeutic target in inflammatory diseases

The cGAS–STING signalling pathway has emerged as a key mediator of inflammation in the settings of infection, cellular stress and tissue damage. Underlying this broad involvement of the cGAS–STING pathway is its capacity to sense and regulate the cellular response towards microbial and host-derived...

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Podrobná bibliografie
Vydáno v:Nat Rev Immunol
Hlavní autoři: Decout, Alexiane, Katz, Jason D., Venkatraman, Shankar, Ablasser, Andrea
Médium: Artigo
Jazyk:Inglês
Vydáno: Nature Publishing Group UK 2021
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC8029610/
https://ncbi.nlm.nih.gov/pubmed/33833439
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41577-021-00524-z
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