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The cGAS–STING pathway as a therapeutic target in inflammatory diseases

The cGAS–STING signalling pathway has emerged as a key mediator of inflammation in the settings of infection, cellular stress and tissue damage. Underlying this broad involvement of the cGAS–STING pathway is its capacity to sense and regulate the cellular response towards microbial and host-derived...

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Bibliografske podrobnosti
izdano v:Nat Rev Immunol
Main Authors: Decout, Alexiane, Katz, Jason D., Venkatraman, Shankar, Ablasser, Andrea
Format: Artigo
Jezik:Inglês
Izdano: Nature Publishing Group UK 2021
Teme:
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC8029610/
https://ncbi.nlm.nih.gov/pubmed/33833439
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41577-021-00524-z
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