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The Role of Pyruvate Kinase M2 in Cancer Metabolism

The M2 isoform of pyruvate kinase is expressed preferentially in cancer cells over other pyruvate kinase isoforms. PKM2 is unique in its ability to be regulated allosterically by nutrients and growth signaling pathways, allowing cells to adapt their metabolic program to match physiological needs in...

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Detalles Bibliográficos
Publicado en:Brain Pathol
Main Authors: Liu, Vivian M., Vander Heiden, Matthew G.
Formato: Artigo
Idioma:Inglês
Publicado: John Wiley and Sons Inc. 2015
Assuntos:
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC8029046/
https://ncbi.nlm.nih.gov/pubmed/26526946
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/bpa.12311
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