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Identification of small molecule inhibitors of pyruvate kinase M2
A common feature of tumors arising from diverse tissue types is a reliance on aerobic glycolysis for glucose metabolism. This metabolic difference between cancer cells and normal cells could be exploited for therapeutic benefit in patients. Cancer cells universally express the M2 isoform of the glyc...
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| Main Authors: | , , , , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado: |
2009
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| Assuntos: | |
| Acceso en liña: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2823991/ https://ncbi.nlm.nih.gov/pubmed/20005212 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bcp.2009.12.003 |
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