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The Role of Pyruvate Kinase M2 in Cancer Metabolism
The M2 isoform of pyruvate kinase is expressed preferentially in cancer cells over other pyruvate kinase isoforms. PKM2 is unique in its ability to be regulated allosterically by nutrients and growth signaling pathways, allowing cells to adapt their metabolic program to match physiological needs in...
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| Udgivet i: | Brain Pathol |
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| Main Authors: | , |
| Format: | Artigo |
| Sprog: | Inglês |
| Udgivet: |
John Wiley and Sons Inc.
2015
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| Fag: | |
| Online adgang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC8029046/ https://ncbi.nlm.nih.gov/pubmed/26526946 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/bpa.12311 |
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