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The Role of Pyruvate Kinase M2 in Cancer Metabolism

The M2 isoform of pyruvate kinase is expressed preferentially in cancer cells over other pyruvate kinase isoforms. PKM2 is unique in its ability to be regulated allosterically by nutrients and growth signaling pathways, allowing cells to adapt their metabolic program to match physiological needs in...

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書誌詳細
出版年:Brain Pathol
主要な著者: Liu, Vivian M., Vander Heiden, Matthew G.
フォーマット: Artigo
言語:Inglês
出版事項: John Wiley and Sons Inc. 2015
主題:
オンライン・アクセス:https://ncbi.nlm.nih.gov/pmc/articles/PMC8029046/
https://ncbi.nlm.nih.gov/pubmed/26526946
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/bpa.12311
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