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Mutation-specific non-canonical pathway of PTEN as a distinct therapeutic target for glioblastoma

PTEN is one of the most frequently altered tumor suppressor genes in malignant tumors. The dominant-negative effect of PTEN alteration suggests that the aberrant function of PTEN mutation might be more disastrous than deletion, the most frequent genomic event in glioblastoma (GBM). This study aimed...

पूर्ण विवरण

में बचाया:
ग्रंथसूची विवरण
में प्रकाशित:Cell Death Dis
मुख्य लेखकों: Choi, Seung Won, Lee, Yeri, Shin, Kayoung, Koo, Harim, Kim, Donggeon, Sa, Jason K., Cho, Hee Jin, Shin, Hye-mi, Lee, Se Jeong, Kim, Hyunho, Chung, Seok, Shin, Jihye, Lee, Cheolju, Nam, Do-Hyun
स्वरूप: Artigo
भाषा:Inglês
प्रकाशित: Nature Publishing Group UK 2021
विषय:
ऑनलाइन पहुंच:https://ncbi.nlm.nih.gov/pmc/articles/PMC8027895/
https://ncbi.nlm.nih.gov/pubmed/33828082
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41419-021-03657-0
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