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Novel Semi-Replicative Retroviral Vector Mediated Double Suicide Gene Transfer Enhances Antitumor Effects in Patient-Derived Glioblastoma Models

As glioblastomas are mostly localized infiltrative lesions, gene therapy based on the retroviral replicating vector (RRV) system is considered an attractive strategy. Combinations of multiple suicide genes can circumvent the limitations associated with each gene, achieving direct and synergistic cyt...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Veröffentlicht in:Cancers (Basel)
Hauptverfasser: Lee, Mijeong, Kim, Yeon-Soo, Lee, Kyoungmin, Kang, Moonkyung, Shin, Hyemi, Oh, Jeong-Woo, Koo, Harim, Kim, Donggeon, Kim, Yejin, Kong, Doo-Sik, Nam, Do-Hyun, Lee, Hye Won
Format: Artigo
Sprache:Inglês
Veröffentlicht: MDPI 2019
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6721803/
https://ncbi.nlm.nih.gov/pubmed/31370279
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/cancers11081090
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