Novel Semi-Replicative Retroviral Vector Mediated Double Suicide Gene Transfer Enhances Antitumor Effects in Patient-Derived Glioblastoma Models

As glioblastomas are mostly localized infiltrative lesions, gene therapy based on the retroviral replicating vector (RRV) system is considered an attractive strategy. Combinations of multiple suicide genes can circumvent the limitations associated with each gene, achieving direct and synergistic cyt...

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Detalhes bibliográficos
Publicado no:Cancers (Basel)
Main Authors: Lee, Mijeong, Kim, Yeon-Soo, Lee, Kyoungmin, Kang, Moonkyung, Shin, Hyemi, Oh, Jeong-Woo, Koo, Harim, Kim, Donggeon, Kim, Yejin, Kong, Doo-Sik, Nam, Do-Hyun, Lee, Hye Won
Formato: Artigo
Idioma:Inglês
Publicado em: MDPI 2019
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6721803/
https://ncbi.nlm.nih.gov/pubmed/31370279
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/cancers11081090
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