PIP4K2A as a negative regulator of PI3K in PTEN-deficient glioblastoma

Glioblastoma (GBM) is the most malignant brain tumor with profound genomic alterations. Tumor suppressor genes regulate multiple signaling networks that restrict cellular proliferation and present barriers to malignant transformation. While bona fide tumor suppressors such as PTEN and TP53 often und...

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Detalhes bibliográficos
Publicado no:J Exp Med
Main Authors: Shin, Yong Jae, Sa, Jason K., Lee, Yeri, Kim, Donggeon, Chang, Nakho, Cho, Hee Jin, Son, Miseol, Oh, Michael Y.T., Shin, Kayoung, Lee, Jin-Ku, Park, Jiwon, Jo, Yoon Kyung, Kim, Misuk, Paddison, Patrick J., Tergaonkar, Vinay, Lee, Jeongwu, Nam, Do-Hyun
Formato: Artigo
Idioma:Inglês
Publicado em: Rockefeller University Press 2019
Assuntos:
Research Articles
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6504209/
https://ncbi.nlm.nih.gov/pubmed/30898893
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1084/jem.20172170
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