Exploring the putative mechanism of allosteric modulations by mixed-action kappa/mu opioid receptor bitopic modulators

The modulation and selectivity mechanisms of seven mixed-action kappa opioid receptor (KOR)/mu opioid receptor (MOR) bitopic modulators were explored. Molecular modeling results indicated that the ‘message’ moiety of seven bitopic modulators shared the same binding mode with the orthosteric site of...

Descripció completa

Guardat en:
Dades bibliogràfiques
Publicat a:Future Med Chem
Autors principals: Wang, Huiqun, Cao, Danni, Gillespie, James C, Mendez, Rolando E, Selley, Dana E, Liu-Chen, Lee-Yuan, Zhang, Yan
Format: Artigo
Idioma:Inglês
Publicat: Newlands Press Ltd 2021
Matèries:
Research Article
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC8027703/
https://ncbi.nlm.nih.gov/pubmed/33590767
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4155/fmc-2020-0308
Etiquetes: Afegir etiqueta
Sense etiquetes, Sigues el primer a etiquetar aquest registre!

Ítems similars